Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or research is crucial for making sure the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound while in the synthesis of imatinib, a drug that targets particular kinds of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their study is crucial for optimizing the manufacturing system and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): 3-(4-Nitro-1-oxo-1 Lapatinib is applied to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the remedy of breast most cancers. Various intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers including ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have several purposes, including antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for style two 7-dihydro-4-oxo-1H-pymol[2 diabetic issues that inhibits the enzyme DPP-four to manage blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of varied gluconic acid derivatives, which might be Employed in food items, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication utilized to manage kind two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).